Blog Post

Juvederm vs. Restylane vs. Radiesse: A Guide to the Fillers We Carry

You’ve probably noticed there’s no single “dermal filler.” Walk into any medspa and you’ll hear brand names tossed around, Juvederm, Restylane, RHA, Radiesse, with very little explanation of why one gets chosen over another. This guide is a clear look at the filler families we carry at Radiance and what makes each one suited to different areas of your face.

If you’re newer to fillers entirely, our post on how dermal fillers work covers the basics of what fillers are made of and what they do. This guide picks up where that one leaves off.

Juvederm vs. Restylane vs. Radiesse at Radiance

How your injector actually chooses a filler

The decision isn’t about brand loyalty. It’s about matching the filler’s physical properties to the job. Each filler has a different thickness, flexibility, and degree of lift, and those properties determine where it performs best.

A filler placed in your cheeks needs to hold structure against gravity. A filler in your lips needs to move naturally when you talk and smile. Your injector evaluates the area, your anatomy, and the result you’re after, then selects the product that fits. The goal is always natural — you should look like yourself, just rested and well.

One thing worth knowing before you dive into brand names: most of what we use is fully reversible. If something needs adjusting, it can be dissolved. But more importantly, the best results come from starting conservatively and building over time. It’s easier to add than to overdo it, and a good injector would rather have you come back for a touch-up than walk out wondering if it’s too much.

A consultation at Radiance starts with your goals, not a product recommendation.

Skincare consultations are complimentary at Radiance

Hyaluronic acid fillers: the foundation

Most of the fillers we use are built on hyaluronic acid (HA), a substance your skin already produces naturally. HA fillers are soft, gel-like, and reversible. If you’re unhappy with a result or want an adjustment, an enzyme called hyaluronidase can dissolve the filler. That safety net is one reason HA fillers remain the most popular category.

Within HA fillers, the differences come down to how the gel is manufactured. Each brand engineers its gel differently, and those choices are what make one filler better suited to lips and another to cheeks.

Restylane

Restylane was one of the first HA fillers on the market and remains a go-to for precise, natural-looking correction. We carry Restylane L and Restylane Lyft.

Restylane L works well for moderate lines around the nose and mouth (nasolabial folds) and for subtle lip enhancement. Its firmer gel structure holds shape without spreading, which gives your injector precise control over placement.

Restylane Lyft handles deeper volume: cheeks, midface, and the backs of the hands. It’s the only HA filler FDA-cleared specifically for hand rejuvenation, making veins and tendons less prominent.

Results from Restylane products typically last 6 to 12 months depending on the area treated and your individual metabolism.

RHA Collection

RHA stands for Resilient Hyaluronic Acid. This newer line (Redensity, RHA 2, RHA 3, and RHA 4) is built to move with your face rather than sitting rigidly beneath the skin.

That flexibility makes RHA a strong fit for dynamic areas: around the mouth, in the lips, and along the nasolabial folds where your face is constantly in motion. The result looks natural mid-expression, not just at rest.

RHA 4 is the firmest in the line and can provide real lift in the cheeks and midface while still moving naturally. Duration is comparable to Restylane, roughly 6 to 15 months.

Revanesse

Revanesse Versa+ and Lips+ have built a following for their smooth injection feel and less post-treatment swelling. The gel flows easily during injection but holds its shape once placed.

Versa+ works well for nasolabial folds, marionette lines, and cheek contouring. Lips+ is made for lip augmentation, providing volume and definition with less of the swelling that sometimes follows lip injections.

Juvederm Voluma

Juvederm’s Vycross technology creates a smooth, cohesive gel that integrates well into tissue. We carry Voluma, made for deep cheek and midface volume. It provides noticeable lift and can last up to 24 months, one of the longest durations among HA fillers.

Voluma tends to be a go-to when the goal is restoring cheek contour that’s thinned over time. The lift is structural but still looks like you, not like you had something done.

Beyond hyaluronic acid

Radiesse

Radiesse is made of calcium hydroxylapatite (CaHA) microspheres, a substance that occurs naturally in bone. It provides immediate volume on injection, then does something the HA fillers don’t: the CaHA microspheres stimulate your skin’s own collagen production over the following weeks and months. So you get the instant fill, and then your skin continues to rebuild structure on its own.

Radiesse works well for deeper facial folds and areas where structural support matters, like the jawline and cheeks. It’s not reversible the way HA fillers are, so it’s typically a better fit once you’ve had filler before and know what result you want. Duration is approximately 12 to 18 months.

Sculptra

Sculptra works differently from everything above. Rather than filling a specific line or fold, it stimulates collagen production across a broader area. The active ingredient, poly-L-lactic acid (PLLA), works gradually over a series of sessions. Results develop over weeks, not the same day.

That makes Sculptra a better fit when the goal is overall volume restoration rather than targeted correction, especially for hollow cheeks, temples, and areas where volume loss leaves you looking tired. Results can last two years or more. We have a full breakdown in our post on what Sculptra is and how it works.

Know which area you want to treat? Book a complimentary consultation — your injector will walk you through the best options for that spot.

Which filler is right for you?

There’s no single answer, and that’s actually the point. The right filler depends on the area being treated, the result you want, your facial structure, and whether you’ve had filler before. Your injector weighs all of this during your consultation.

At Radiance, you sit down with the person who will actually perform your treatment. Not a coordinator, not a salesperson. Our injectors have over 20 years of experience between them, and nearly 200 Google reviews at close to a 5.0 back that up. That conversation is where the real decision gets made, and it’s based on what’s right for your face, not what’s on promotion.

Even if you’re not ready to treat, a consultation gives you a clear plan: which filler, which areas, what to expect, and what it costs. You walk out with answers, not a sales pitch.

Book a complimentary consultation whenever you’re ready. No pressure, no obligation.

Ready to get started? Book a complimentary consultation — we’ll walk through your options.